Find the best rates for hotels in and around Picayune, MS, and throughout Mississippi. Best of all, there is no extra fee for booking a room.

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Picayune, MS Hotels

Comfort Inn Picayune
550 South Lofton Dr.
Picayune, MS 39466
Nightly Rates: ( 89.99 - 109.99 )
2 Star
Within 2 miles of historic district and antique shops. Within 1 hour of New Orleans, LA and Gulfport casinos. Free high speed Internet access in all rooms. City - I-59 @ Exit 4...see more

Days Inn - Picayune
450 South Lofton Ave.
Picayune, MS 39466
Nightly Rates: ( 79.95 - 79.95 )
2 Star
Beautifully appointed hotel within one hour of Biloxi casinos and New Orleans Business district, Expressway...see more